Some Good News about Depression and Anti-oxidants!

We've all heard how much money Americans spend on anti-depressants every year, and how much of them wind up in our water supply.

What a boon to the Earth and to humanity for a natural, non-toxic substance to be found just as effective in the treatment of this condition.  The fantastic news is that we may have stumbled on just such a discovery.

After my mother's onset of dementia, I became clinically depressed.  She lived with us, and my children were 10 and 1 at the time. I was put on Wellbutrin, which messed with my brain in unhealthy ways. I couldn't think clearly, I could no longer multitask or plan meals or appointments for the next few days. I got off the meds and natural remedies. Based on my experience I would not recommend prescription drugs to anyone, unless they had exhausted other methods of treatment.

Below is good news!

Antioxidants as antidepressants: fact or fiction?

Scapagnini G, Davinelli S, Drago F, De Lorenzo A, Oriani G. 2012, Jun 1st

Source : Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy.

Depression is a medical condition with a complex biological pattern of aetiology, involving genetic and epigenetic factors, along with different environmental stressors. Recent evidence suggests that oxidative stress processes might play a relevant role in the pathogenic mechanism(s) underlying many major psychiatric disorders, including depression.

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Reactive oxygen and nitrogen species have been shown to modulate levels and activity of noradrenaline (norepinephrine), serotonin, dopamine and glutamate, the principal neurotransmitters involved in the neurobiology of depression. Major depression has been associated with lowered concentrations of several endogenous antioxidant compounds, such as vitamin E, zinc and coenzyme Q10, or enzymes, such as glutathione peroxidase, and with an impairment of the total antioxidant status.

Additionally, curcumin, the yellow pigment of curry, has been shown to strongly interfere with neuronal redox homeostasis in the CNS and to possess antidepressant activity in various animal models of depression, also thanks to its ability to inhibit monoamine oxidases.

There is an urgent need to develop better tolerated and more effective treatments for depressive disorders and several antioxidant treatments appear promising and deserve further study.

Be Well! ♥

Astaxanthin - A Gift from the Sea

The great variety of plants, herbs, roots and food which have been discovered to contain powerful plant chemicals is truly astounding. Astaxanthin, a compound found in plants such as algae and animals such as salmon and krill, an ocean dwelling crustacean similar to shrimp, is one of those compounds. It is a member of a group of plant pigments called carotenoids and is therefore related to such compounds as beta-carotene, lutein, lycopene and vitamin A.

These pigments are highly antioxidative and some of them are functionally important in vision and eye health.

Protection from oxidative damage: Due to astaxanthin’s unique structure, it can actually insert itself into a cell membrane where it can then effectively perform its role as protector of that membrane from reactive oxygen species (ROS).

As oxidative damage can be a mechanism for the development of a variety of disease processes, astaxanthin could prove to be useful in many clinical applications.

Endothelial dysfunction is a common aspect of the process that eventually can lead to cardiovascular disease. In models of hypertension in stroke prone laboratory animals, astaxanthin has been shown to not only improve endothelial function but also display antithrombotic and antihypertensive properties, thus decreasing risk factors associated with heart disease pathophysiology. Astaxanthin also improved insulin resistance, the common predecessor or diabetes.

Additionally, in a human study, this red colored, lipid soluble pigment also increased HDL while significantly reducing triglycerides, therefore addressing other risk factors in cardiovascular disease.

Exercise and athletics: Improved sports performance and athletic capacity has been an interesting facet of astaxanthin research. For instance, in competitive cyclists, astaxanthin ingestion was associated with significant improvements in time trials as well as power output.

Muscle endurance and strength also improved with its supplementation.

Oxidative stress can be a significant issue in overweight and obese individuals as they have a higher capacity of generating lipid peroxidation than those of typical body composition. Throw in exercise and the incidence of oxidative damage dramatically increases in this population. Astaxanthin was able to decrease lipid peroxidation and various markers in this vulnerable segment of society.

Boosting immune function: Improved immune function and immune response are also beneficial effects of astaxanthin supplementation where it stimulated cell-mediated and humoral immune function in lab animals, while in another study it modulated inflammatory cytokines, including IL-1β, IL-6, and cyclooxygenase (COX)-2, thus inhibiting colitis and colitis-associated colon carcinogenesis.

Neuroprotection: Finally, astaxanthin has demonstrated possible neuroprotective properties as well suggesting it may be useful in those with potential to develop neurodegenerative conditions such as Alzheimer’s or dementia.  by Michael Fuhrman D.C.

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XanthOmega™

In addition to its rich phospholipids, omega–3s, and astaxanthin, XanthOmega™ also naturally contains several other antioxidants including, canthaxanthin, β–carotene, vitamin E and trans–retinol vitamin A. These antioxidants offer benefits of their own while also protecting this nutrient–dense oil from oxidation.

Designs for Health's XanthOmega™ Krill Oil is made using a unique cold–extraction process that converts it into stable oil. This process protects the lipids from alteration and avoids peroxidation. It is free of heavy metals and organohalide pollutants, making it extremely pure. This product does not cause reflux or regurgitation commonly experienced by those consuming regular fish oil supplements.

*These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure or prevent any disease.

Fortified with increased levels of astaxanthin for expanded health benefits

The amount of the powerful antioxidant astaxanthin in XanthOmega™ Krill Oil has been increased from 1.5 mg to 12 mg per serving to help achieve optimal benefits from this potent carotenoid.

What are Krill?  Krill are tiny crustaceans found in the sea and make up the world's largest animal biomass. The oil extracted from krill is rich in the omega–3 fatty acids EPA and DHA.

This updated version is considered to be a virgin krill oil, the purest form available, with higher phospholipid bioavailability, enhancing the absorption of one of krill's shining features, the powerful antioxidant astaxanthin.

In summary, many studies suggest that the benefits of this level of astaxanthin may include:

  1. Powerful antioxidant
  2. Cardiovascular health – helping to promote healthy lipid profiles; potential anti–hypertensive
  3. Sports performance – increasing muscle endurance and reducing exercise–induced muscle damage
  4. Eye support – Reducing eye fatigue and improving visual acuity[5]
  5. Supporting skin health – protecting against UVA–induced aging, as in skin sagging and wrinkles
  6. Anti–inflammatory
  7. Gastric health support – helping to reduce gastric inflammation and reflux symptoms

CAUTION: This product contains Krill Oil. DO NOT take if you are allergic to Shellfish.

Foods with Vitamin E

Like many nutrients, instead of taking them in the form of a supplement, it's best to get our Vitamin E from foods.  This way we get all the other benefits that particular food has to offer, since happily Mother Nature loads each food with more than one beneficial ingredient! I thought this table might come in handy when you're shopping, or planning your meal to include Vitamin E.

Selected Food Sources of Vitamin E (Alpha-Tocopherol) mg per serving Percent DV*

 Wheat germ oil 1 Tbs.                20.31
Sunflower seeds- dry roasted 1 oz.

7.437

Almonds- dry roasted 1 oz.                6.834
Sunflower oil 1 Tbs.                5.628
Safflower oil 1 Tbs.                4.625
Hazelnuts - dry roasted 1 oz.                4.322
Peanut butter 2 Tbs.                2.915
Peanuts - dry roasted 1 oz.                2.211
corn oil 1 Tbs.                1.910
Olive oil 1 Tbs.                1.910
Spinach, boiled ½ c.                1.910
Broccoli, boiled chopped ½ c.                1.26
Soybean oil 1 Tbs.                1.16
Kiwifruit 1 medium                1.16
Mango -sliced ½ c.                0.74
Tomato - raw 1 medium                0.74
Spinach - raw 1 c.                0.63